{"id":2618,"date":"2025-02-26T09:55:07","date_gmt":"2025-02-26T09:55:07","guid":{"rendered":"https:\/\/genosophy.gr\/product\/prolispi-kardiaggeiakon-nisimaton\/"},"modified":"2025-04-25T08:23:04","modified_gmt":"2025-04-25T08:23:04","slug":"prolispi-kardiaggeiakon-nisimaton","status":"publish","type":"product","link":"https:\/\/genosophy.gr\/en\/product\/prolispi-kardiaggeiakon-nisimaton\/","title":{"rendered":"Cardiovascular Disease Prevention"},"content":{"rendered":"<p>Cardiovascular diseases are the leading cause of death worldwide. The genetic test for the prevention of cardiovascular diseases detects mutations that affect factors such as:<\/p>\n<ul>\n<li><strong>Blood pressure<\/strong><\/li>\n<li><strong>Levels of cholesterol and triglycerides<\/strong><\/li>\n<li><strong>Thrombotic predisposition<\/strong><\/li>\n<li><strong>Inflammatory responses associated with atherosclerosis<\/strong><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Which Genes Are Tested?<\/h3>\n<h4>Polygenic Hypertension Panel<\/h4>\n<ul>\n<li><strong>ACE (Angiotensin-Converting Enzyme):<\/strong> Regulates blood pressure through the renin-angiotensin system.<\/li>\n<li><strong>AGT (Angiotensinogen):<\/strong> Involved in blood pressure regulation and associated with an increased risk of hypertension.<\/li>\n<li><strong>NOS3 (Endothelial Nitric Oxide Synthase):<\/strong> Regulates the dilation of blood vessels.<\/li>\n<li><strong>ADD1 (Adducin 1):<\/strong> Influences sodium reabsorption in the kidneys and is associated with hypertension.<\/li>\n<\/ul>\n<h4>Polygenic Dyslipidemia Panel<\/h4>\n<ul>\n<li><strong>APOE (Apolipoprotein E):<\/strong> Regulates lipid metabolism and is linked to high LDL levels and atherosclerosis.<\/li>\n<li><strong>LDLR (Low-Density Lipoprotein Receptor):<\/strong> Affects the removal of LDL cholesterol from the blood.<\/li>\n<li><strong>PCSK9 (Proprotein Convertase Subtilisin\/Kexin Type 9):<\/strong> Regulates the degradation of LDL receptors and influences cholesterol levels.<\/li>\n<li><strong>CETP (Cholesteryl Ester Transfer Protein):<\/strong> Involved in HDL cholesterol metabolism.<\/li>\n<\/ul>\n<h4>Genetic Test for Thrombosis<\/h4>\n<ul>\n<li><strong>F5 (Factor V Leiden):<\/strong> A mutation that increases the predisposition to thrombosis.<\/li>\n<li><strong>F2 (Prothrombin, G20210A):<\/strong> Increases the likelihood of thrombosis.<\/li>\n<li><strong>MTHFR (Methylenetetrahydrofolate Reductase):<\/strong> Associated with elevated homocysteine levels, which heighten the risk of vascular diseases.<\/li>\n<li><strong>SERPINE1 (PAI-1):<\/strong> Regulates fibrinolysis and is linked to increased thrombogenicity.<\/li>\n<\/ul>\n<h4>Genetic Test for Cardiovascular Diseases<\/h4>\n<ul>\n<li><strong>LPA (Lipoprotein(a)):<\/strong> Elevated levels are associated with a high risk of cardiovascular diseases.<\/li>\n<li><strong>ABCA1 (ATP-Binding Cassette Transporter A1):<\/strong> Regulates cholesterol transport and affects HDL levels.<\/li>\n<li><strong>KCNJ11 (Potassium Voltage-Gated Channel):<\/strong> Associated with metabolic disorders that impact heart function.<\/li>\n<li><strong>SCARB1 (Scavenger Receptor Class B Type 1):<\/strong> Influences the uptake of HDL cholesterol by the liver.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Why Choose This Test?<\/h3>\n<p>Identifying these genetic predispositions allows for personalized interventions, such as tailored diets, targeted medications (e.g., statins, anticoagulants), and close medical monitoring, all aimed at reducing the risk of cardiovascular events.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cardiovascular diseases are the leading cause of death worldwide. The genetic test for the prevention of cardiovascular diseases detects mutations that affect factors such as: Blood pressure Levels of cholesterol and triglycerides Thrombotic predisposition Inflammatory responses associated with atherosclerosis &nbsp; Which Genes Are Tested? Polygenic Hypertension Panel ACE (Angiotensin-Converting Enzyme): Regulates blood pressure through the [&hellip;]<\/p>\n","protected":false},"featured_media":2461,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[74],"product_tag":[],"class_list":{"0":"post-2618","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-cardio-en","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product\/2618","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media\/2461"}],"wp:attachment":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media?parent=2618"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_brand?post=2618"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_cat?post=2618"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_tag?post=2618"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}