{"id":2652,"date":"2025-02-26T11:43:49","date_gmt":"2025-02-26T11:43:49","guid":{"rendered":"https:\/\/genosophy.gr\/product\/nosos-crohn\/"},"modified":"2025-04-24T14:26:23","modified_gmt":"2025-04-24T14:26:23","slug":"nosos-crohn","status":"publish","type":"product","link":"https:\/\/genosophy.gr\/en\/product\/nosos-crohn\/","title":{"rendered":"Crohn&#8217;s Disease"},"content":{"rendered":"<h3>What is Crohn&#8217;s Disease?<\/h3>\n<p>Crohn&#8217;s disease is a chronic inflammatory condition of the gastrointestinal tract and is classified among the Inflammatory Bowel Diseases (IBD). It causes inflammation that can affect any part of the digestive system\u2014from the mouth to the anus\u2014although it most often affects the small intestine and the colon.<\/p>\n<h3>About the Test<\/h3>\n<p>The genetic test for Crohn&#8217;s disease analyzes 40 genetic loci and uses a specialized algorithm to calculate the genetic risk for developing Crohn&#8217;s disease. It will confirm whether you have the genes associated with an increased risk of the disease. Individuals with a high genetic risk, as identified through this specific test, have about 4.44 times greater likelihood of developing Crohn&#8217;s disease compared to those with a low genetic risk. The analysis results are ready within 5-6 weeks from the receipt of the samples at the laboratory.<\/p>\n<h3>The Genes of Crohn&#8217;s Disease<\/h3>\n<p>Crohn&#8217;s disease has a strong genetic component, as individuals with a family history of the disease are at increased risk of developing it. There are several genes that have been linked to Crohn&#8217;s disease, and mutations in these genes may contribute to its development. The main genes involved in Crohn&#8217;s disease include:<\/p>\n<ul>\n<li><strong>NOD2 (or CARD15)<\/strong><\/li>\n<li><strong>ATG16L1<\/strong><\/li>\n<li><strong>IL23R<\/strong><\/li>\n<\/ul>\n<p>Although these genes increase the risk, Crohn&#8217;s disease is not entirely genetically determined. Environmental factors (such as smoking, diet, and infections) play an important role in triggering the disease in genetically predisposed individuals.<\/p>\n<h3>How Can Genetic Testing for Crohn&#8217;s Disease Help?<\/h3>\n<p>Genetic testing can help by determining:<\/p>\n<ul>\n<li>Whether there are mutations in genes that may lead to an increased risk of developing the disease.<\/li>\n<li>Whether you are at risk of developing Crohn&#8217;s disease at any point in your life.<\/li>\n<li>Whether you carry the genes for Crohn&#8217;s disease, which could be passed on to your children.<\/li>\n<\/ul>\n<h3>Why is the Genetic Test for Crohn&#8217;s Disease a Good Option?<\/h3>\n<p>The genetic test offers several specific advantages:<\/p>\n<ul>\n<li>Individuals with a family history of the disease can undergo genetic testing to determine their risk of developing Crohn&#8217;s disease.<\/li>\n<li>The presence of mutations in genes may increase the likelihood of developing the disease.<\/li>\n<li>The genetic test can aid in targeted treatment, guiding doctors in the choice of medications.<\/li>\n<li>It may help clarify the diagnosis, especially when symptoms resemble other inflammatory bowel conditions, such as ulcerative colitis.<\/li>\n<li>Identifying genetic variations in high-risk individuals can lead to monitoring and preventive measures (e.g., lifestyle changes, avoiding smoking).<\/li>\n<\/ul>\n<h3>Genetic Testing for Crohn&#8217;s Disease in Children<\/h3>\n<p>Genetic testing in children is useful if many family members (e.g., parents or siblings) have been diagnosed with Crohn&#8217;s disease or other inflammatory bowel diseases. It is also beneficial in conjunction with clinical and laboratory examinations in cases where a child exhibits symptoms such as chronic diarrhea, abdominal pain, unexplained weight loss, or anemia.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0397 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03c4\u03bf\u03c5 Crohn \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b7\u03c2 \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03bd\u03ae\u03ba\u03b5\u03b9 \u03c3\u03c4\u03b9\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03b9\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 (\u0399nflammatory Bowel Diseases, IBD).<\/p>\n","protected":false},"featured_media":2465,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[86],"product_tag":[],"class_list":{"0":"post-2652","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptic-en","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product\/2652","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media\/2465"}],"wp:attachment":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media?parent=2652"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_brand?post=2652"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_cat?post=2652"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_tag?post=2652"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}