{"id":2748,"date":"2025-03-18T12:04:54","date_gmt":"2025-03-18T12:04:54","guid":{"rendered":"https:\/\/genosophy.gr\/product\/elkodis-kolitidi\/"},"modified":"2025-04-24T13:15:17","modified_gmt":"2025-04-24T13:15:17","slug":"elkodis-kolitidi","status":"publish","type":"product","link":"https:\/\/genosophy.gr\/en\/product\/elkodis-kolitidi\/","title":{"rendered":"Ulcerative Colitis"},"content":{"rendered":"<p>According to published studies\u00b9, individuals in the <strong>top 30% of the polygenic risk score (PRS)<\/strong> have a <strong>4.44 times greater likelihood<\/strong> of developing <strong>ulcerative colitis<\/strong> compared to those in the lowest genetic risk group\u2014especially if they follow an unhealthy dietary pattern. However, <strong>a personalized diet<\/strong>, <strong>avoiding smoking<\/strong>, <strong>regular exercise<\/strong>, and <strong>maintaining a healthy weight<\/strong> can significantly <strong>reduce the risk<\/strong> of developing the disease and help <strong>manage symptoms<\/strong>.<\/p>\n<p>The <strong>GENOSOPHY\u00ae genetic test<\/strong> offers an advanced assessment of the <strong>genetic risk for ulcerative colitis<\/strong>, analyzing <strong>42 genetic loci<\/strong> through GENOSOPHY\u00ae\u2019s <strong>award-winning algorithm<\/strong>, ensuring <strong>high accuracy<\/strong> in risk prediction.<\/p>\n<h3>Conditions Covered by the Test<\/h3>\n<p>This test determines the <strong>relative risk<\/strong> for <strong>ulcerative colitis<\/strong> in the general population and is recommended for:<\/p>\n<ul>\n<li>Individuals with a <strong>family history<\/strong> of ulcerative colitis<\/li>\n<li>People who <strong>present symptoms<\/strong> related to the condition and wish to assess their genetic risk<\/li>\n<\/ul>\n<h3>Clinical Benefits of GENOSOPHY\u00ae\u2019s Polygenic Risk Score<\/h3>\n<h4>Diagnosis<\/h4>\n<ul>\n<li>More <strong>accurate estimation of genetic risk<\/strong> for ulcerative colitis, providing <strong>complementary insights<\/strong> for clinical evaluation<\/li>\n<\/ul>\n<h4>Prognosis<\/h4>\n<ul>\n<li>Enables <strong>early selection of preventive strategies<\/strong> through specialized protocols\u00b2, with recent studies showing that a <strong>healthy lifestyle can halve the genetic risk<\/strong> for the disease\u00b9<\/li>\n<\/ul>\n<h4>Management<\/h4>\n<ul>\n<li>Supports the development of <strong>personalized dietary and lifestyle interventions<\/strong> for optimal disease control<\/li>\n<\/ul>\n<h3>Testing Process<\/h3>\n<ul>\n<li><strong>Saliva sample collection<\/strong><\/li>\n<li><strong>Analysis of 42 genetic variants<\/strong> and <strong>risk calculation<\/strong> via the award-winning GENOSOPHY\u00ae algorithm<\/li>\n<li><strong>Results delivered within 5\u20136 weeks<\/strong><\/li>\n<\/ul>\n<h3>Supplementary Services<\/h3>\n<p>Based on your results and genetic profile, <strong>GENOSOPHY\u00ae<\/strong> offers the following services to <strong>maximize the impact<\/strong> of your preventive plan:<\/p>\n<ul>\n<li><strong>Genetic counseling<\/strong><\/li>\n<li><strong>Customized nutrition plan based on your genetic profile<\/strong><\/li>\n<li><strong>Nutritional consultation<\/strong><\/li>\n<\/ul>\n<h3>Selected References<\/h3>\n<ol>\n<li>Sun Y et al., <em>Am J Gastroenterol<\/em> 2023 Mar 1;118(3):511\u2013522. DOI: 10.14309\/ajg.0000000000002180<\/li>\n<\/ol>\n<p>Pardali et al., <em>Metabol Open<\/em> 2024 Dec 30;25:100342. DOI: 10.1016\/j.metop.2024.100342<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to published studies\u00b9, individuals in the top 30% of the polygenic risk score (PRS) have a 4.44 times greater likelihood of developing ulcerative colitis compared to those in the lowest genetic risk group\u2014especially if they follow an unhealthy dietary pattern. However, a personalized diet, avoiding smoking, regular exercise, and maintaining a healthy weight can [&hellip;]<\/p>\n","protected":false},"featured_media":2465,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[87],"product_tag":[],"class_list":{"0":"post-2748","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptic-ipiresies-gia-epaggelmaties-en","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product\/2748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media\/2465"}],"wp:attachment":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media?parent=2748"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_brand?post=2748"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_cat?post=2748"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_tag?post=2748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}