{"id":2750,"date":"2025-03-18T12:04:53","date_gmt":"2025-03-18T12:04:53","guid":{"rendered":"https:\/\/genosophy.gr\/product\/koiliokaki-disaneksa-sti-glouteni\/"},"modified":"2025-04-24T13:16:28","modified_gmt":"2025-04-24T13:16:28","slug":"koiliokaki-disaneksa-sti-glouteni","status":"publish","type":"product","link":"https:\/\/genosophy.gr\/en\/product\/koiliokaki-disaneksa-sti-glouteni\/","title":{"rendered":"Celiac Disease \u2013 Gluten Intolerance"},"content":{"rendered":"

According to published studies\u00b9, polygenic risk score (PRS) evaluation<\/strong> offers greater accuracy<\/strong> in assessing celiac disease risk compared to traditional HLA-DQ analysis<\/strong> (which is also included in the test).<\/p>\n

The GENOSOPHY\u00ae genetic test<\/strong> for celiac disease risk assessment is based on the analysis of 46 genetic variants<\/strong> that contribute to the development of the condition. The test is performed using GENOSOPHY\u00ae\u2019s award-winning algorithm<\/strong>, ensuring high reliability<\/strong> in risk evaluation.<\/p>\n

Conditions Covered by the Test<\/h3>\n

This test estimates relative risk for celiac disease<\/strong> and is recommended for:<\/p>\n

    \n
  • Individuals with a family history<\/strong> of celiac disease or other risk factors<\/li>\n
  • People showing symptoms such as gastrointestinal disturbances<\/strong>, unexplained weight loss<\/strong>, or anemia<\/strong>, who wish to explore their genetic predisposition<\/strong><\/li>\n
  • Individuals with autoimmune diseases<\/strong>, as celiac disease may co-exist with other autoimmune conditions<\/li>\n<\/ul>\n

    Clinical Benefits of GENOSOPHY\u00ae\u2019s Polygenic Risk Score<\/strong><\/p>\n

    Diagnosis<\/h4>\n
      \n
    • More accurate estimation of genetic risk for celiac disease, offering complementary information to standard diagnostic tests<\/li>\n<\/ul>\n

      Prognosis<\/h4>\n
        \n
      • The polygenic score can also serve as an exclusion tool<\/strong>\u2014in the reference study, no cases of celiac disease<\/strong> were observed in individuals with risk scores below the 38th percentile<\/strong><\/li>\n<\/ul>\n

        Management<\/h4>\n
          \n
        • Targeted guidance<\/strong> for additional diagnostic procedures, avoiding unnecessary endoscopies<\/strong> in individuals at low genetic risk<\/li>\n
        • Enables a personalized approach<\/strong> to managing celiac disease<\/li>\n<\/ul>\n

          Testing Process<\/h3>\n
            \n
          • Saliva sample collection<\/strong><\/li>\n
          • Analysis of 46 genetic loci<\/strong> and calculation of relative risk using the GENOSOPHY\u00ae algorithm<\/strong><\/li>\n
          • Results available in 5\u20136 weeks<\/strong><\/li>\n<\/ul>\n

            Supplementary Services<\/h3>\n

            Based on each individual\u2019s genetic profile, GENOSOPHY\u00ae also offers:<\/p>\n

              \n
            • Genetic counseling<\/strong><\/li>\n
            • Diet plan based on genetic results<\/strong><\/li>\n
            • Nutritional consulting<\/strong><\/li>\n<\/ul>\n

              References<\/h3>\n
                \n
              1. Sharp et al., Am J Gastroenterol<\/em> 2020;115(11):1839\u20131847 \/ DOI: 10.1111\/apt.15826<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

                According to published studies\u00b9, polygenic risk score (PRS) evaluation offers greater accuracy in assessing celiac disease risk compared to traditional HLA-DQ analysis (which is also included in the test). The GENOSOPHY\u00ae genetic test for celiac disease risk assessment is based on the analysis of 46 genetic variants that contribute to the development of the condition. […]<\/p>\n","protected":false},"featured_media":2465,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[87],"product_tag":[],"class_list":{"0":"post-2750","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptic-ipiresies-gia-epaggelmaties-en","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product\/2750","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media\/2465"}],"wp:attachment":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media?parent=2750"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_brand?post=2750"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_cat?post=2750"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_tag?post=2750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}