{"id":2752,"date":"2025-03-18T12:04:56","date_gmt":"2025-03-18T12:04:56","guid":{"rendered":"https:\/\/genosophy.gr\/product\/nosos-crohn-2\/"},"modified":"2025-04-24T13:13:22","modified_gmt":"2025-04-24T13:13:22","slug":"nosos-crohn-2","status":"publish","type":"product","link":"https:\/\/genosophy.gr\/en\/product\/nosos-crohn-2\/","title":{"rendered":"Crohn&#8217;s Disease"},"content":{"rendered":"<p>According to published studies\u00b9, individuals with a <strong>high genetic risk<\/strong> (top 30% of the population) are <strong>approximately 4 times more likely<\/strong> to develop <strong>Crohn\u2019s disease<\/strong> compared to those at low genetic risk, especially if they follow an unhealthy dietary pattern. However, <strong>personalized nutrition<\/strong>, <strong>smoking cessation<\/strong>, <strong>regular physical activity<\/strong>, and <strong>maintaining a healthy body weight<\/strong> can significantly reduce the risk of developing the disease and help manage symptoms.<\/p>\n<p>The <strong>GENOSOPHY\u00ae genetic test<\/strong> offers an <strong>advanced genetic screening<\/strong> for assessing Crohn\u2019s disease risk. The test combines <strong>40 genetic loci<\/strong> with GENOSOPHY\u00ae\u2019s <strong>award-winning algorithm<\/strong>, ensuring <strong>high reliability<\/strong> in predicting genetic risk.<\/p>\n<h3>Conditions Covered by the Test<\/h3>\n<p>This test estimates the <strong>relative risk for Crohn\u2019s disease<\/strong> and is recommended for:<\/p>\n<ul>\n<li>Individuals with a <strong>family history<\/strong> of Crohn\u2019s disease<\/li>\n<li>People with <strong>symptoms related to Crohn\u2019s<\/strong> who wish to assess their <strong>genetic predisposition<\/strong><\/li>\n<\/ul>\n<h3>Clinical Benefits of GENOSOPHY\u00ae&#8217;s Polygenic Risk Score<\/h3>\n<h4>Diagnosis<\/h4>\n<ul>\n<li>More accurate estimation of <strong>genetic risk for Crohn\u2019s disease<\/strong>, offering valuable complementary information to existing diagnostic procedures<\/li>\n<\/ul>\n<h4>Prognosis<\/h4>\n<ul>\n<li>Ability to design <strong>preventive strategies<\/strong> through specialized protocols\u00b2<\/li>\n<li>Studies show that a <strong>healthy lifestyle<\/strong> may <strong>halve<\/strong> the risk of disease, even in genetically predisposed individuals\u00b9<\/li>\n<\/ul>\n<h4>Management<\/h4>\n<ul>\n<li>Design of <strong>personalized interventions<\/strong> in diet and lifestyle for more effective disease management<\/li>\n<\/ul>\n<h3>Testing Process<\/h3>\n<ul>\n<li><strong>Saliva sample collection<\/strong><\/li>\n<li>Analysis of <strong>40 genetic loci<\/strong> and calculation of relative risk using the <strong>GENOSOPHY\u00ae algorithm<\/strong><\/li>\n<li><strong>Results delivered in 5\u20136 weeks<\/strong><\/li>\n<\/ul>\n<h3>Supplementary Services<\/h3>\n<p>Based on each individual\u2019s genetic test results and profile, GENOSOPHY\u00ae offers:<\/p>\n<ul>\n<li><strong>Genetic counseling<\/strong><\/li>\n<li><strong>Personalized dietary plans<\/strong><\/li>\n<li><strong>Nutritional consulting<\/strong><\/li>\n<\/ul>\n<h3>References<\/h3>\n<ol>\n<li>Sun Y et al., <em>Am J Gastroenterol<\/em> 2023 Mar 1;118(3):511\u2013522. DOI: 10.14309\/ajg.0000000000002180<\/li>\n<li>Pardali et al., <em>Metabol Open<\/em> 2024 Dec 30;25:100342. DOI: 10.1016\/j.metop.2024.100342<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>According to published studies\u00b9, individuals with a high genetic risk (top 30% of the population) are approximately 4 times more likely to develop Crohn\u2019s disease compared to those at low genetic risk, especially if they follow an unhealthy dietary pattern. However, personalized nutrition, smoking cessation, regular physical activity, and maintaining a healthy body weight can [&hellip;]<\/p>\n","protected":false},"featured_media":2465,"template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[87],"product_tag":[],"class_list":{"0":"post-2752","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptic-ipiresies-gia-epaggelmaties-en","8":"first","9":"instock","10":"taxable","11":"shipping-taxable","12":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product\/2752","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media\/2465"}],"wp:attachment":[{"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/media?parent=2752"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_brand?post=2752"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_cat?post=2752"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/genosophy.gr\/en\/wp-json\/wp\/v2\/product_tag?post=2752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}