Γενετικός Έλεγχος Για Διαβήτη Κύησης και Έλεγχος Θρομβώσεων

Genetic Risk Assessment for Gestational Diabetes & Thrombosis

According to recent studies, women in the top 10% of polygenic risk score (PRS) are twice as likely to develop gestational diabetes mellitus (GDM) compared to women with a low genetic risk. Additionally, the test includes 11 thrombosis-related genetic variants (as described in the cardio section), which is particularly important for women with a history of miscarriages or familial thromboembolic events, offering a comprehensive, personalized approach to pregnancy care.

The GENOSOPHY® test analyzes 50 genetic variants related to GDM using the award-winning GENOSOPHY® algorithm, plus 11 additional variants associated with thrombotic risk, ensuring a holistic assessment of maternal health.

Who is this test for?

Recommended for:
• Women planning a pregnancy who want to assess their genetic risk profile
• Women with a family history of GDM or thromboembolic events
• Women with recurrent pregnancy loss, where thrombosis screening is clinically relevant

Clinical Benefits of the GENOSOPHY® Polygenic Risk Score

Diagnosis

Identification of women with high genetic risk, allowing for early medical monitoring and intervention

Prognosis

Reliable risk estimation for pregnancy complications, including GDM and thrombosis

Management

Personalized lifestyle and dietary strategies for prevention
Guidance on anticoagulant therapy (e.g., low-molecular-weight heparin) in high-risk cases

Test Procedure

Saliva sample collection
Analysis of 50 genetic variants for GDM and 11 for thrombosis
Results delivered in 5–6 weeks

Additional Services

Based on the test results, GENOSOPHY® offers:
• Genetic counseling
• Personalized meal planning based on genetic profile
• Nutritional consultation

Key Reference

Huvinen et al., Diabetologia 2022; 65(8):1291-1301.
DOI: 10.1007/s00125-022-05712-7