Recent studies indicate that individuals in the top 10% of genetic risk for obesity (based on polygenic risk score) may have a BMI up to 5 units higher compared to low-risk individuals—especially in the context of limited physical activity¹. Additionally, people with a high genetic predisposition to depression are up to 5 times more likely to develop the condition if their body weight is unhealthy².
The GENOSOPHY® Genetic Test combines 201 genetic variants with its award-winning algorithm, ensuring high accuracy in estimating genetic susceptibility to obesity and its related outcomes.
The test is recommended for:
• Individuals struggling with weight management despite healthy diet and exercise habits
• People experiencing mood fluctuations or depression and seeking to explore the link between weight and mental health
• Individuals interested in a personalized approach to obesity medication selection
| Module | # of Variants | Clinical Utility |
| Obesity Risk | 97 | Risk assessment for high BMI and obesity predisposition |
| Weight Regain | 24 | Prediction of weight regain likelihood after weight loss |
| Starch Metabolism | 9 | Evaluation of amylase enzyme activity and its interaction with carbohydrate intake |
| Depression & Eating Behavior | 56 | Genetic risk for depression and interaction with BMI |
| Gen ACTIVE | 9 | Exercise type optimization for effective weight control |
| OB-MED | 7 | Prediction of medication response (Liraglutide, Topiramate, Orlistat, Sibutramine) |
Based on each individual’s genetic profile, GENOSOPHY® also provides:
• Genetic counseling
• Personalized nutrition plan
• Targeted dietetic and lifestyle consultations
